Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Hotel located steps from Buffalo Music Hall of Fame

Choose dates to view prices

Mon, Apr 6
Tue, Apr 7
April 2026
May 2026
In the heart of downtown Buffalo, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR offers a warm welcome with a free breakfast buffet and modern amenities. Connect to in-room WiFi, stay active at the gym, or take advantage of dry cleaning/laundry services. Previous guests rave about the helpful staff.
Excellent

Popular amenities

  • Free WiFi
  • Connecting rooms available
  • Air conditioning
  • Gym
  • Laundry facilities

Main amenities (9)

  • Daily housekeeping
  • Fitness center
  • Business center
  • 24-hour front desk
  • Front-desk safe
  • Vending machine
  • Laundry service
  • Self-serve laundry
  • Luggage storage

For families (6)

  • Children stay free
  • Free cribs/infant beds
  • Microwave
  • Connecting/adjoining rooms available
  • Private bathroom
  • Separate bedroom
$104 nightly
$121 total
Apr 5 - Apr 6
Total with taxes and fees

Room options

Showing 4 of 4 rooms
Combined shower/tub, eco-friendly toiletries, hair dryer, towels
Standard Room | 1 bedroom, in-room safe, desk, laptop workspace
1 bedroom, in-room safe, desk, laptop workspace
1 bedroom, in-room safe, desk, laptop workspace

Standard Room

Wonderful
  • 500 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed
Combined shower/tub, eco-friendly toiletries, hair dryer, towels
Suite, 1 Bedroom | 1 bedroom, in-room safe, desk, laptop workspace
1 bedroom, in-room safe, desk, laptop workspace
1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom

Excellent
  • City view
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
1 bedroom, in-room safe, desk, laptop workspace
Combined shower/tub, eco-friendly toiletries, hair dryer, towels
1 bedroom, in-room safe, desk, laptop workspace
1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

Exceptional
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
1 bedroom, in-room safe, desk, laptop workspace
Combined shower/tub, eco-friendly toiletries, hair dryer, towels
1 bedroom, in-room safe, desk, laptop workspace
1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

Wonderful
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed

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About the neighborhood

Map
601 Main St, Buffalo, NY, 14203

What's nearby

  • Chippewa District - 1 min walk - 0.0 km
  • Shea's Performing Arts Center - 2 min walk - 0.2 km
  • Road Less Traveled Theater - 2 min walk - 0.2 km
  • Buffalo Niagara Convention Center - 5 min walk - 0.5 km
  • Niagara Square - 6 min walk - 0.6 km

Getting around

  • Buffalo Niagara Intl. Airport (BUF) - 21 min drive
  • Niagara Falls, NY (IAG-Niagara Falls Intl.) - 30 min drive
  • Buffalo-Depew Station - 17 min drive
  • Buffalo-Exchange Street Station - 18 min walk
  • Niagara Falls Station - 27 min drive
  • Fountain Plaza Station - 1 min walk
  • Lafayette Square Station - 5 min walk
  • Church Station - 9 min walk

Restaurants

  • ‪Bada Bing - ‬2 min walk
  • ‪Big Ditch Brewing Company - ‬4 min walk
  • ‪Tap House Pub & Grill - ‬4 min walk
  • ‪Lucky Day Whiskey Bar - ‬4 min walk
  • ‪Starbucks - ‬4 min walk

About this property

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

When you stay at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG, you'll be in a fantastic location, just a 5-minute walk from Market Arcade Building and Buffalo Music Hall of Fame. Guests can visit the fitness center for a workout, and free perks include WiFi and buffet breakfast daily between 6:00 AM and 10:00 AM. Also, Shea's Performing Arts Center and CEPA Gallery are within just a 10-minute walk. Fellow travelers love the helpful staff. Public transportation is just a short walk: Fountain Plaza Station is steps away and Lafayette Square Station is 5 minutes.

At a glance

Hotel size

    • 146 rooms
    • Arranged over 7 floors

Arriving/Leaving

    • Check-in start time: 3:00 PM; Check-in end time: anytime
    • Contactless check-in available
    • Express check-out available
    • Minimum check-in age: 21
    • Check-out time is 11 AM
    • Contactless check-out available

Special check-in instructions

    • Front desk staff will greet guests on arrival at the property
    • Information provided by the property may be translated using automated translation tools

Required at check-in

    • Credit card, debit card, or cash deposit required for incidental charges
    • Government-issued photo ID may be required
    • Minimum check-in age is 21

Children

    • Children (18 years old and younger) stay free when occupying the parent or guardian's room, using existing bedding

Pets

    • Pets not allowed
    • Service animals welcome

Internet

    • Free WiFi in public areas
    • Free WiFi in rooms

Parking

    • Wheelchair-accessible parking and van parking on site
    • Onsite garage
    • Offsite parking within 500 ft (USD 16.00 per day)

Other information

    • Smoke-free property

Property amenities

Food and drink

  • Free buffet breakfast each morning 6:00 AM–10:00 AM

Traveling with children

  • Children stay free (see details)

What to do

  • Golfing nearby

Working away

  • Business center

Services

  • 24-hour front desk
  • Dry cleaning/laundry services
  • Luggage storage

Facilities

  • Safe-deposit box at front desk
  • Fitness center
  • Vegetarian dining options
  • At least 80% lighting from LEDs
  • Comprehensive food waste policy

Accessibility

  • Wheelchair-accessible bathroom vanity
  • Elevator
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible parking
  • Assistive listening devices available
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible van parking
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible fitness center
  • Wheelchair-accessible business center
  • Wheelchair-accessible restaurant
  • Visual alarms in hallways
  • Handrails in stairways
  • Hand-held showerheads
  • Portable shower seat
  • Raised toilet seat
  • Lowered electrical outlets in bathroom
  • Height-adjustable showerhead
  • Grab bar near toilet
  • Grab bar in shower
  • Roll-in shower
  • Lever door handles

Room amenities

Be entertained

  • 49-inch TV
  • Cable TV channels

Home comfort

  • Air conditioning (climate-controlled) and heating
  • Coffee/tea maker
  • Iron/ironing board

Sleep well

  • Blackout drapes/curtains
  • Double sofa bed
  • Free crib/infant bed
  • Bed sheets provided

What to enjoy

  • Separate living room

Freshen up

  • Private bathroom
  • Shower/tub combination
  • Eco-friendly toiletries
  • Hair dryer
  • Towels

Stay connected

  • Desk
  • Free WiFi
  • Free local calls

Food and drink

  • Refrigerator
  • Microwave

More

  • Daily housekeeping
  • In-room safe
  • Connecting/adjoining rooms available
  • Eco-friendly toiletries
  • Bulk dispenser for toiletries
  • LED light bulbs
  • Guidebooks/recommendations
  • Restaurant dining guide

Fees & policies

Parking

  • Parking is available nearby and costs USD 16.00 per day (500 ft away)

Policies

The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.
Only registered guests are allowed in the guestrooms.
This property uses eco-friendly cleaning products.
Guests can rest easy knowing there's a fire extinguisher, a smoke detector, and window guards on site.
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation.
This property accepts credit cards. Cash is not accepted.
Credit cards accepted: Visa, Mastercard, American Express, Discover, Diners Club, JCB International, Carte Blanche
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).
Please note that cultural norms and guest policies may differ by country and by property. The policies listed are provided by the property.

Also known as

Holiday Inn Express Buffalo Downtown Hotel
Comfort Suites Hotel Downtown
Comfort Suites Downtown Hotel Buffalo
Comfort Suites Downtown Buffalo
Comfort Suites Downtown Buffalo Hotel
Comfort Suites Buffalo
Buffalo Comfort Suites
Holiday Inn Express Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown Medical CTR
Holiday Inn Express Suites Buffalo Downtown Medical CTR by IHG

Frequently asked questions

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offer free cancellation for a full refund?

Yes, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG does have fully refundable room rates available to book on our site. If you’ve booked a fully refundable room rate, this can be cancelled up to a few days before check-in depending on the property's cancellation policy. Just make sure to check this property's cancellation policy for the exact terms and conditions.

Are pets allowed at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Sorry, pets aren't allowed, but service animals are welcome.

What are the check-in and check-out times at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Check-in start time: 3:00 PM; Check-in end time: anytime. Check-out time is 11 AM. Express check-out and contactless check-in and check-out are available.

Is there an onsite casino at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, this hotel doesn't have a casino, but Seneca Buffalo Creek Casino (3-min drive) and Hamburg Gaming at the Fairgrounds (19-min drive) are both nearby.

What is there to do at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG and nearby?

Maintain your daily exercise routine at the gym.

What's the area around Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG like?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is a short 1-minute walk from Fountain Plaza Station and 7 minutes' walk from Buffalo Niagara Convention Center.

Have a question?

Get instant answers with AI powered search of property information and reviews.

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

8.6

Excellent

8.8

Cleanliness

8.8

Location

8.8

Staff & service

8.6

Property conditions & facilities

What guests liked

  • Breakfast was consistently good, with many guests praising its quality and variety. (40 reviews)
  • Convenient dining options were available nearby, with some guests walking to nearby restaurants and enjoying good breakfast options. (8 reviews)
AI Sparkle IconFrom real guest reviews summarized by AI.

Popular mentions

RoomService staffParkingBreakfastLocationRestaurantBedBathroomShowerLobby
Verified

10/10 Exceptional

Very clean and friendly staff
Ellen, 1-night trip
Verified

10/10 Exceptional

Good Stay All Around
Joseph, 1-night trip
Verified

10/10 Exceptional

Rooms were large. Breakfast was good and very friendly and helpful staff
RYAN, 1-night trip
Verified

8/10 Very good

Rooms were clean and the breakfast was very good. Traveled with our kids and 4 grandkids. They had a great time
Daniel, 1-night trip
Verified

10/10 Exceptional

Staff was pleasant, our suite was clean and well kept. Great breakfast!
Tricia, 1-night trip
Verified

10/10 Exceptional

In town for a concert, staff very helpful with recommendations for travel and dining
Jennifer, 1-night trip
Verified

10/10 Exceptional

Clean, nice staff, good breakfast
Daniel, 3-night trip
Verified

10/10 Exceptional

Front desk was amazing
Daron, 1-night trip
Verified

2/10 Poor

Staff was absolutely terrible
john, 3-night trip
Verified

10/10 Exceptional

.
Marty, 1-night trip
Verified

6/10 Good

Room noisy as we were on Main Street side with train When we went at 8a for breakfast it was wiped out
Patricia, 1-night trip
Verified

10/10 Exceptional

yes
Ed, 1-night trip
Verified

8/10 Very good

Location
Frank, 1-night trip
Verified

10/10 Exceptional

Staff was warming and friendly!
Emma, 1-night trip
Verified

2/10 Poor

This has got to be the worst place I've ever stayed in , rude staff and no help what's o ever , I will never stay here again let alone a holiday in in the near future .. dirty room and parking is 2 blocks away
William, 1-night trip
Verified

6/10 Good

Eddy the front desk guy was great . Really helped me out and had alot of knowledge.
Peter, 1-night trip
Verified

10/10 Exceptional

We were there for the the worlds largest disco. It made it a super convenient walk to the convention center. Great room too!! Friendly staff, we would love to stay again. Thank you!!
annmarie, 1-night trip
Verified

6/10 Good

Staff very good. Hotel quite worn in parts; i.e getting random electric shocks from door handles and light switches. Food smell in room everytime fans active (food hall next door). Beds comfy and plenty of space in room/suite. Complimentary breakfast okay with fairly small choice. A fair price for what we paid considering nearby alternatives were more expensive and we were located near numerous bars and restaurants.
Lee, 4-night trip
Verified

10/10 Exceptional

Great Stay!

Very nice room, good breakfast and friendly staff. Would stay again.
Todd, 2-night trip
Verified

10/10 Exceptional

Night staff was super friendly and welcoming! Rooms are spacious and comfortable
Kimberly, 1-night trip
Verified

10/10 Exceptional

Perfect for what we were there for.
Amber, 1-night trip
Verified

10/10 Exceptional

Everyone was phenomenal
Mary Kramer, 2-night trip
Verified

10/10 Exceptional

Mario was awesome! Good area. Easy to get to arena.
Henry, 1-night trip
Verified

6/10 Good

Staff bey nice, especially BW! Had a
Brad, 2-night trip
Verified

8/10 Very good

The breakfast was exactly as expected The bed was wonderful
Jessalynn, 1-night trip