Experience luxury and convenience near iconic attractions like Busch Stadium. Take a break from exploring to indulge your senses with great food and drink.
Nestled in the heart of St. Louis, 21C Museum Hotel St Louis offers a luxurious retreat with an indoor pool, coffee shop/cafe, and gym. Indulge in a massage at the spa or enjoy billiards at the bar while relishing cooked-to-order breakfast options.
Reviews
9.29.2 out of 10
Wonderful
Popular amenities
Bar
24/7 front desk
Main amenities
Daily housekeeping
Restaurant and bar/lounge
Indoor pool
Breakfast available
Fitness center
Steam room
Valet parking
Room service
Coffee shop/cafe
Spa services
Business center
Meeting rooms
Feel at home
Premium TV channels
Daily housekeeping
Espresso maker
Blackout drapes/curtains
Pets allowed
Elevator
The current price is $193
$193
includes taxes & fees
$165 per night
Feb 25 - Feb 26
Room options
Available filters for rooms
Showing 9 of 9 rooms
Loft, 2 Queen Beds
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Bathrobes
Hair dryer
Private bathroom
Sleeps 4
2 Queen Beds
View all photos for Deluxe Room, 1 King Bed
Deluxe Room, 1 King Bed
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Bathrobes
Hair dryer
Private bathroom
309 sq ft
Sleeps 2
1 King Bed
View all photos for Room (Bunk Bed)
Room (Bunk Bed)
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout drapes/curtains
Bathrobes
Hair dryer
Sleeps 2
1 Twin Bunk Bed
View all photos for Deluxe Double Room, 2 Queen Beds
Deluxe Double Room, 2 Queen Beds
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Shower/tub combination
Hair dryer
Private bathroom
369 sq ft
Sleeps 4
2 Queen Beds
Deluxe Room, Accessible (Accessible)
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Bathrobes
Hair dryer
Private bathroom
Sleeps 2
1 King Bed
View all photos for Room, 1 King Bed, Corner
Room, 1 King Bed, Corner
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Bathrobes
Hair dryer
Private bathroom
326 sq ft
City view
Sleeps 2
1 King Bed
View all photos for Suite, 1 King Bed
Suite, 1 King Bed
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Bathrobes
Hair dryer
Private bathroom
Sleeps 2
1 King Bed
View all photos for Deluxe Suite, 1 King Bed
Deluxe Suite, 1 King Bed
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout drapes/curtains
Bathrobes
Hair dryer
Private bathroom
Sleeps 2
1 King Bed
View all photos for Luxury Double Room, 2 Queen Beds
St. Louis Lambert Intl. Airport (STL) - 26 min drive
St. Louis, MO (SUS-Spirit of St. Louis) - 32 min drive
St. Louis Gateway Station - 14 min walk
Kirkwood Station - 24 min drive
8th and Pine Station - 13 min walk
Convention Center Station - 16 min walk
Stadium Station - 19 min walk
Restaurants
Rosalita's Cantina - 6 min walk
Grand Hall Lounge Union Station - 11 min walk
Hair of the Dog - 7 min walk
Peabody Lounge - 6 min walk
Medina Mediterranean Grill - 5 min walk
About this property
21C Museum Hotel St Louis
21C Museum Hotel St Louis puts you in a great location, within just a 10-minute walk of City Museum and Enterprise Center. Guests indulge in massages, then grab a bite to eat at the coffee shop/cafe. Other features of this luxurious hotel include an indoor pool, a bar/lounge, and a fitness center. Fellow travelers say great things about the pool and helpful staff. Public transportation is close by: 8th and Pine Station is just 13 minutes by foot.
Languages
English
At a glance
Hotel size
104 rooms
Arriving/Leaving
Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21
Check-out time is 11:00 AM
Special check-in instructions
Front desk staff will greet guests on arrival at the property
Required at check-in
Credit card, debit card, or cash deposit required for incidental charges
Government-issued photo ID may be required
Minimum check-in age is 21
Children
No cribs (infant beds)
Pets
Pets allowed (dogs only)*
Service animals welcome
Internet
Free WiFi in public areas
Free WiFi in rooms
Parking
Onsite valet parking (USD 45 per day; includes in/out privileges)
Other information
Smoke-free property
Property amenities
Food and drink
Cooked-to-order breakfast (surcharge) each morning 6:30 AM–1:00 PM
Guests can pamper themselves by indulging in the onsite spa services. Services include massages.
Fees & policies
Mandatory fees
You'll be asked to pay the following charges by the property at check-in or check-out. Fees may include applicable taxes:
Service fee: USD 5 per accommodation, per stay
Optional extras
Cooked-to-order breakfast is offered for an extra charge of approximately USD 10 to 25 per person
Pets
Service animals exempt from fees
Pets are allowed for an extra charge of USD 100 per accommodation, per stay
Parking
Valet parking costs USD 45 per day with in/out privileges
Pool, spa, & gym (if applicable)
Reservations are required for massage services and can be made by contacting the property before arrival at the number on the booking confirmation
Policies
Guests can rest easy knowing there's outdoor lighting on site.
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).
This property accepts credit cards. Cash is not accepted.
Property Registration Number 832174967
Also known as
21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)
Frequently asked questions
Does 21C Museum Hotel St Louis offer free cancellation for a full refund?
Yes, 21C Museum Hotel St Louis does have fully refundable room rates available to book on our site. If you’ve booked a fully refundable room rate, this can be cancelled up to a few days before check-in depending on the property's cancellation policy. Just make sure to check this property's cancellation policy for the exact terms and conditions.
Is there a pool at 21C Museum Hotel St Louis ?
Yes, there's an indoor pool.
Are pets allowed at 21C Museum Hotel St Louis ?
Yes, dogs are welcome. There's a charge of USD 100 per accommodation, per stay. Service animals are exempt from fees.
Is parking offered on site at 21C Museum Hotel St Louis ?
Yes. Valet parking costs USD 45 per day.
What are the check-in and check-out times at 21C Museum Hotel St Louis ?
Check-in start time: 4:00 PM; Check-in end time: 11:00 AM. Check-out time is 11:00 AM.
Is there an onsite casino at 21C Museum Hotel St Louis ?
No, this hotel doesn't have a casino, but Horseshoe St. Louis Casino (3-min drive) and Casino Queen (4-min drive) are both nearby.
What is there to do at 21C Museum Hotel St Louis and nearby?
21C Museum Hotel St Louis has an indoor pool and a steam room, as well as spa services.
Are there restaurants at or near 21C Museum Hotel St Louis ?
Yes, there's an onsite restaurant.
What's the area around 21C Museum Hotel St Louis like?
21C Museum Hotel St Louis is in Downtown West, a short 12-minute walk from St. Louis Union Station and 18 minutes' walk from Busch Stadium. Travelers love the hotel's prime location.
Reviews
9.2
Wonderful
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
9.4/10
Cleanliness
9.2/10
Staff & service
9.2/10
Amenities
9.4/10
Property conditions & facilities
9.2/10
Eco-friendliness
Reviews
10/10 Exceptional
Feb 9, 2025
Colleen
Colleen, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
Feb 4, 2025
Shannon
Shannon, 2-night trip with friends
Verified Hotels.com guest review
10/10 Exceptional
Feb 1, 2025
Verified traveler
1-night trip with friends
Verified Hotels.com guest review
10/10 Exceptional
Jan 27, 2025
Verified traveler
1-night trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 25, 2025
Convenient & Clean
Beautiful hotel with a perfect location! Staff was very friendly and vallet was so fast!
Bailey
Bailey, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 23, 2025
CRISTINA
CRISTINA, 3-night trip with friends
Verified Hotels.com guest review
10/10 Exceptional
Jan 19, 2025
Leslie
Leslie, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 18, 2025
perfect for couples
We stayed at 21C for an overnight getaway. The check in was seamless- the staff was very friendly. Our room was beautiful and clean (was missing body wash but it was quickly rectified). The robes were luxurious, a really nice touch. We enjoyed all of the amenities at the hotel; the pool, hot tub and sauna (all clean and enjoyable), the "nightcap at the museum" and the art museum as well. We had a reservation at the restaurant (best burger in town!) and went back to the bar for dessert and drinks later in the evening (I wish dessert was better). In the morning we went to the coffee shop for breakfast (so delicious!). Everything we needed was right there. The only negatives were; the pillows were not comfortable, the cups in the room for coffee were disposable and not mugs (I prefer mugs and that's what's shown on the website) and I wish parking wasn't so expensive. Overall, a really wonderful experience- we will definitely stay at the 21C again.
Amy
Amy, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 18, 2025
Stay here instead of a conference hotel!
Lovely two-night stay at the 21c STL. Very reasonable room price, nice bar and very good restaurant, comfy "gameroom" for hanging out. Thoughtful art and interior design as you would expect from a 21c property. Yummy coffee/tea/breakfast shop.
Verified traveler
2-night trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 14, 2025
KELLIE
KELLIE, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 14, 2025
Staci
Staci, 2-night trip
Verified Hotels.com guest review
8/10 Very Good
Jan 13, 2025
Verified traveler
1-night trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 12, 2025
Perfection!
10 out of 10. This will be our new STL staycation when we need a night away. Restaurant was fabulous - food drinks and service all outstanding - then strolled thru the museum for some culture with a drink bf calling it a night. Next time would love to enjoy the pool, hot tub and spa!
Becky
Becky, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 12, 2025
Great stay in unique hotel
I had a great stay. The property was very unique. I loved the museum and decor. The restaurant and bar had great food. I also enjoyed the fitness and pool areas. If I’m in the city I would stay again.
Patrice
Patrice, 2-night business trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 9, 2025
Irna
Irna, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 8, 2025
Stephan
Stephan, 1-night business trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 7, 2025
Alexander
Alexander, 2-night trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 7, 2025
Dimonica
Dimonica, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 4, 2025
Highly recommend!
Beautiful property! Loved the decor. The rooms we chose was large (2 beds) and comfortable. Very clean and modern. Great bar! Mason is a great bartender!
regine
regine, 1-night trip with friends
Verified Hotels.com guest review
10/10 Exceptional
Jan 2, 2025
Verified traveler
1-night business trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 2, 2025
Monique
Monique, 2-night trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 2, 2025
Bell
Bell, 2-night family trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 2, 2025
Christopher
Christopher, 1-night family trip
Verified Hotels.com guest review
10/10 Exceptional
Jan 1, 2025
Great stay
Fabulous hotel, decor amazing, loved the museum, room was perfect